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Lethality in a Murine Model of Pulmonary Anthrax is Reduced by Combining Nuclear Transport Modifier with Antimicrobial Therapy

BACKGROUND: In the last ten years, bioterrorism has become a serious threat and challenge to public health worldwide. Pulmonary anthrax caused by airborne Bacillus anthracis spores is a life- threatening disease often refractory to antimicrobial therapy. Inhaled spores germinate into vegetative form...

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Autors principals: Veach, Ruth Ann, Zienkiewicz, Jozef, Collins, Robert D., Hawiger, Jacek
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266913/
https://ncbi.nlm.nih.gov/pubmed/22291977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030527
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