CBX7 is a tumor suppressor in mice and humans

The CBX7 gene encodes a polycomb group protein that is known to be downregulated in many types of human cancers, although the role of this protein in carcinogenesis remains unclear. To shed light on this issue, we generated mice null for Cbx7. Mouse embryonic fibroblasts derived from these mice had...

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Detalhes bibliográficos
Main Authors: Forzati, Floriana, Federico, Antonella, Pallante, Pierlorenzo, Abbate, Adele, Esposito, Francesco, Malapelle, Umberto, Sepe, Romina, Palma, Giuseppe, Troncone, Giancarlo, Scarfò, Marzia, Arra, Claudio, Fedele, Monica, Fusco, Alfredo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266782/
https://ncbi.nlm.nih.gov/pubmed/22214847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI58620
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