Transglutaminase 2 is secreted from smooth muscle cells by transamidation-dependent microparticle formation

Transglutaminase 2 (TG2) is a pleiotropic enzyme involved in both intra- and extracellular processes. In the extracellular matrix, TG2 stabilizes the matrix by both covalent cross-linking and disulfide isomerase activity. These functions become especially apparent during matrix remodeling as seen in...

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Bibliographic Details
Main Authors: van den Akker, Jeroen, van Weert, Angela, Afink, Gijs, Bakker, Erik N. T. P., van der Pol, Edwin, Böing, Anita N., Nieuwland, Rienk, VanBavel, Ed
Format: Artigo
Language:Inglês
Published: Springer Vienna 2011
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266506/
https://ncbi.nlm.nih.gov/pubmed/21830119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00726-011-1010-3
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