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Exposure of the lysine in the gamma chain dodecapeptide of human fibrinogen is not enhanced by adsorption to poly(ethylene terephthalate) as measured by biotinylation and mass spectrometry

Conformational changes in adsorbed fibrinogen may enhance the exposure of platelet adhesive sites that are inaccessible in solution. To test this hypothesis, mass spectrometric methods were developed to quantify chemical modification of lysine residues following adsorption of fibrinogen to biomateri...

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Bibliografski detalji
Glavni autori: Ovod, Vitaliy, Scott, Evan A., Flake, Megan M., Parker, Stanley R., Bateman, Randall J., Elbert, Donald L.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266446/
https://ncbi.nlm.nih.gov/pubmed/22213354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm.a.33285
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