Acquisition of cocaine self-administration in male Sprague-Dawley rats: Effects of cocaine dose but not initial locomotor response to cocaine

RATIONALE: We have previously described a model in which adult outbred male Sprague-Dawley rats are classified as either low or high cocaine responders (LCRs or HCRs, respectively) based on acute cocaine-induced open-field activation. This model revealed important individual differences in cocaine’s...

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Hlavní autoři: Mandt, Bruce H., Johnston, Nickie L., Zahniser, Nancy R., Allen, Richard M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266438/
https://ncbi.nlm.nih.gov/pubmed/21863236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-011-2438-6
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