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P47(phox) IS REQUIRED FOR AFFERENT ARTERIOLAR CONTRACTILE RESPONSES TO ANGIOTENSIN II AND PERFUSION PRESSURE IN MICE

Myogenic and angiotensin contractions of afferent arterioles generate reactive oxygen species. Resistance vessels express NOX-2 and -4. Angiotensin II activates p47(phox)/NOX-2 whereas it downregulates NOX-4. Therefore, we tested the hypothesis that p47(phox) enhances afferent arteriolar angiotensin...

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Autori principali: Lai, En Yin, Solis, Glenn, Luo, Zaiming, Carlstrom, Mattias, Sandberg, Kathryn, Holland, Steven, Wellstein, Anton, Welch, William J., Wilcox, Christopher S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266435/
https://ncbi.nlm.nih.gov/pubmed/22184329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.111.184291
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