Histone Deacetylase 6 (HDAC6) Is an Essential Modifier of Glucocorticoid-Induced Hepatic Gluconeogenesis

In the current study, we investigated the importance of histone deacetylase (HDAC)6 for glucocorticoid receptor–mediated effects on glucose metabolism and its potential as a therapeutic target for the prevention of glucocorticoid-induced diabetes. Dexamethasone-induced hepatic glucose output and glu...

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Autores principales: Winkler, Robin, Benz, Verena, Clemenz, Markus, Bloch, Mandy, Foryst-Ludwig, Anna, Wardat, Sami, Witte, Nicole, Trappiel, Manuela, Namsolleck, Pawel, Mai, Knut, Spranger, Joachim, Matthias, Gabriele, Roloff, Tim, Truee, Oliver, Kappert, Kai, Schupp, Michael, Matthias, Patrick, Kintscher, Ulrich
Formato: Artigo
Lenguaje:Inglês
Publicado: American Diabetes Association 2012
Materias:
Pharmacology and Therapeutics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266407/
https://ncbi.nlm.nih.gov/pubmed/22210316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-0313
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