Low-Frequency Variants in HMGA1 Are Not Associated With Type 2 Diabetes Risk

It has recently been suggested that the low-frequency c.136–14_136–13insC variant in high-mobility group A1 (HMGA1) may strongly contribute to insulin resistance and type 2 diabetes risk. In our study, we attempted to confirm that HMGA1 is a novel type 2 diabetes locus in French Caucasians. The gene...

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Detalhes bibliográficos
Main Authors: Marquez, Marcel, Huyvaert, Marlène, Perry, John R.B., Pearson, Richard D., Falchi, Mario, Morris, Andrew P., Vivequin, Sidonie, Lobbens, Stéphane, Yengo, Loïc, Gaget, Stefan, Pattou, Francois, Poulain-Godefroy, Odile, Charpentier, Guillaume, Carlsson, Lena M.S., Jacobson, Peter, Sjöström, Lars, Lantieri, Olivier, Heude, Barbara, Walley, Andrew, Balkau, Beverley, Marre, Michel, Froguel, Philippe, Cauchi, Stéphane
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2012
Assuntos:
Genetics/Genomes/Proteomics/Metabolomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266400/
https://ncbi.nlm.nih.gov/pubmed/22210315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-0728
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