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Propentofylline decreases tumor growth in a rodent model of glioblastoma multiforme by a direct mechanism on microglia

Glioblastoma multiforme (GBM) is the most common and aggressive primary brain cancer, with a median survival of less than 2 years after diagnosis. The tumor microenvironment plays a critical role in tumor invasion and progression. Microglia and infiltrating macrophages are the most abundant immune c...

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Detalhes bibliográficos
Main Authors: Jacobs, Valerie L., Landry, Russell P., Liu, Yingna, Romero-Sandoval, Edgar Alfonso, De Leo, Joyce A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266380/
https://ncbi.nlm.nih.gov/pubmed/22086978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nor194
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