Networks of intergenic long-range enhancers and snpRNAs drive castration-resistant phenotype of prostate cancer and contribute to pathogenesis of multiple common human disorders

The mechanistic relevance of intergenic disease-associated genetic loci (IDAGL) containing highly statistically significant disease-linked SNPs remains unknown. Here, we present experimental and clinical evidence supporting the importantance of the role of IDAGL in human diseases. A targeted RT-PCR...

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Detalhes bibliográficos
Main Authors: Glinskii, Anna B, Ma, Shuang, Ma, Jun, Grant, Denise, Lim, Chang-Uk, Guest, Ian, Sell, Stewart, Buttyan, Ralph, Glinsky, Gennadi V
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
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Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266183/
https://ncbi.nlm.nih.gov/pubmed/22067658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.20.17842
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