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Natural IgM in immune equilibrium and harnessing their therapeutic potential
Natural IgM antibodies are the constitutively secreted products of B1 cells (CD5(+) in mice and CD20(+)CD27(+)CD43(+) CD70(−) in humans) that have important and diverse roles in health and disease. Whereas the role of natural IgM as first line of defense for protection against invading microbes has...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3266110/ https://ncbi.nlm.nih.gov/pubmed/22262757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102107 |
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