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Integrating genetic and gene expression evidence into genome-wide association analysis of gene sets

Single variant or single gene analyses generally account for only a small proportion of the phenotypic variation in complex traits. Alternatively, gene set or pathway association analyses are playing an increasingly important role in uncovering genetic architectures of complex traits through the ide...

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Hlavní autoři: Xiong, Qing, Ancona, Nicola, Hauser, Elizabeth R., Mukherjee, Sayan, Furey, Terrence S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266045/
https://ncbi.nlm.nih.gov/pubmed/21940837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.124370.111
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