Mithramycin encapsulated in polymeric micelles by microfluidic technology as novel therapeutic protocol for beta-thalassemia

This report shows that the DNA-binding drug, mithramycin, can be efficiently encapsulated in polymeric micelles (PM-MTH), based on Pluronic(®) block copolymers, by a new microfluidic approach. The effect of different production parameters has been investigated for their effect on PM-MTH characterist...

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Detalhes bibliográficos
Main Authors: Capretto, Lorenzo, Mazzitelli, Stefania, Brognara, Eleonora, Lampronti, Ilaria, Carugo, Dario, Hill, Martyn, Zhang, Xunli, Gambari, Roberto, Nastruzzi, Claudio
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2012
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265999/
https://ncbi.nlm.nih.gov/pubmed/22287841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S25657
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