The synaptic vesicle SNARE neuronal Synaptobrevin promotes endolysosomal degradation and prevents neurodegeneration

Soluble NSF attachment protein receptors (SNAREs) are the core proteins in membrane fusion. The neuron-specific synaptic v-SNARE n-syb (neuronal Synaptobrevin) plays a key role during synaptic vesicle exocytosis. In this paper, we report that loss of n-syb caused slow neurodegeneration independent o...

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Autores principales: Haberman, Adam, Williamson, W. Ryan, Epstein, Daniel, Wang, Dong, Rina, Srisha, Meinertzhagen, Ian A., Hiesinger, P. Robin
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2012
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Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265959/
https://ncbi.nlm.nih.gov/pubmed/22270918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201108088
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