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Stabilization of (dG-dC)n.(dG-dC)n in the Z conformation by a crosslinking reaction.

(dG-dC)n.(dG-dC) was converted to the Z conformer by heating in the presence of Mn++n. Reaction of this preparation with the crosslinking reagent, DL-diepoxybutane (DEB), stabilized this conformer so that it retained its structure even when returned to conditions that favored reversion to the B conf...

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Hlavní autoři: Castleman, H, Hanau, L H, Erlanger, B F
Médium: Artigo
Jazyk:Inglês
Vydáno: 1983
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC326592/
https://ncbi.nlm.nih.gov/pubmed/6672768
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