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Dynamics of Amyloid β Fibrils Revealed by Solid-state NMR
We have investigated the site-specific backbone dynamics of mature amyloid β (Aβ) fibrils using solid-state NMR spectroscopy. Overall, the known β-sheet segments and the turn linking these two β-strands exhibit high order parameters between 0.8 and 0.95, suggesting low conformational flexibility. Th...
में बचाया:
| मुख्य लेखकों: | , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
American Society for Biochemistry and Molecular Biology
2012
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3265881/ https://ncbi.nlm.nih.gov/pubmed/22130659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.308619 |
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