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Initiating RNA polymerase II and TIPs as hallmarks of enhancer activity and tissue-specificity

In past years, many efforts were invested to define epigenetic features associated with enhancers of transcription. We propose that both transcription initiation and the H3K4me3 histone modification are among the best hallmarks of active enhancers in several primary tissues and extend the concept of...

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Autori principali: Koch, Frederic, Andrau, Jean-Christophe
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265787/
https://ncbi.nlm.nih.gov/pubmed/22223044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/trns.2.6.18747
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