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Solution versus Gas-Phase Modification of Peptide Cations with NHS-Ester Reagents
A comparison between solution and gas phase modification of primary amine sites in model peptide cations with N-hydroxysuccinimide (NHS) ester reagents is presented. In all peptides, the site of modification in solution was directed to the N-terminus by conducting reactions at pH = 5 whereas, for th...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3265610/ https://ncbi.nlm.nih.gov/pubmed/22081458 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-011-0291-9 |
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