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Solution versus Gas-Phase Modification of Peptide Cations with NHS-Ester Reagents

A comparison between solution and gas phase modification of primary amine sites in model peptide cations with N-hydroxysuccinimide (NHS) ester reagents is presented. In all peptides, the site of modification in solution was directed to the N-terminus by conducting reactions at pH = 5 whereas, for th...

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Библиографические подробности
Главные авторы: Mentinova, Marija, Barefoot, Nathan Z., McLukey, Scott A.
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265610/
https://ncbi.nlm.nih.gov/pubmed/22081458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-011-0291-9
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