Inhibition of Adipogenesis and Induction of Apoptosis and Lipolysis by Stem Bromelain in 3T3-L1 Adipocytes

The phytotherapeutic protein stem bromelain (SBM) is used as an anti-obesity alternative medicine. We show at the cellular level that SBM irreversibly inhibits 3T3-L1 adipocyte differentiation by reducing adipogenic gene expression and induces apoptosis and lipolysis in mature adipocytes. At the mol...

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Main Authors: Dave, Sandeep, Kaur, Naval Jit, Nanduri, Ravikanth, Dkhar, H. Kitdorlang, Kumar, Ashwani, Gupta, Pawan
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265525/
https://ncbi.nlm.nih.gov/pubmed/22292054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030831
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