Superhelicity induces hypersensitivity of a human polypyrimidine . polypurine DNA sequence in the human alpha 2-alpha 1 globin intergenic region to S1 nuclease digestion--high resolution mapping of the clustered cleavage sites.
Supercoiled recombinant DNAs containing the human adult alpha-globin gene region have been probed with nuclease S1 in vitro. While agarose gel electrophoresis showed only one predominant, double-stranded cleavage generated by S1 within 6 kb of human DNA and 4 kb of pBR322 sequence, a high resolution...
Na minha lista:
| Udgivet i: | Nucleic Acids Res |
|---|---|
| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
1983
|
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC326548/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6316277/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/11.22.7899 |
| Tags: |
Ingen Tags, Vær først til at tagge denne postø!
|