Cisplatin Tumor Biodistribution and Efficacy after Intratumoral Injection of a Biodegradable Extended Release Implant

Local delivery of chemotherapeutic drugs has long been recognized as a potential method for reaching high drug doses at the target site while minimizing systemic exposure. Cisplatin is one of the most effective chemotherapeutic agents for the treatment of various tumors; however, its systemic toxici...

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Main Authors: Shikanov, Ariella, Shikanov, Sergey, Vaisman, Boris, Golenser, Jacob, Domb, Abraham J.
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265254/
https://ncbi.nlm.nih.gov/pubmed/22295203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/175054
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