RGD peptide-mediated chitosan-based polymeric micelles targeting delivery for integrin-overexpressing tumor cells

BACKGROUND: Solid tumors need new blood vessels to feed and nourish them as well as to allow tumor cells to escape into the circulation and lodge in other organs, which is termed “angiogenesis.” Some tumor cells within solid tumors can overexpress integrins α(v)β(3) and α(v)β(5), which can specifica...

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Autors principals: Cai, Li-Li, Liu, Ping, Li, Xi, Huang, Xuan, Ye, Yi-Qing, Chen, Feng-Ying, Yuan, Hong, Hu, Fu-Qiang, Du, Yong-Zhong
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2011
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265222/
https://ncbi.nlm.nih.gov/pubmed/22282676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S26670
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