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Calcium- and integrin-binding protein 1 regulates megakaryocyte ploidy, adhesion, and migration
Megakaryocytes are large, polyploid cells that produce platelets. We have previously reported that calcium- and integrin-binding protein 1 (CIB1) regulates endomitosis in Dami cells. To further characterize the role of CIB1 in megakaryopoiesis, we used a Cib1(−/−) mouse model. Cib1(−/−) mice have mo...
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| Glavni autori: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society of Hematology
2012
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3265206/ https://ncbi.nlm.nih.gov/pubmed/22128142 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-04-346098 |
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