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Calcium- and integrin-binding protein 1 regulates megakaryocyte ploidy, adhesion, and migration

Megakaryocytes are large, polyploid cells that produce platelets. We have previously reported that calcium- and integrin-binding protein 1 (CIB1) regulates endomitosis in Dami cells. To further characterize the role of CIB1 in megakaryopoiesis, we used a Cib1(−/−) mouse model. Cib1(−/−) mice have mo...

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Detalhes bibliográficos
Main Authors: Kostyak, John C., Naik, Meghna U., Naik, Ulhas P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265206/
https://ncbi.nlm.nih.gov/pubmed/22128142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-04-346098
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