A site and strand specific nuclease activity with analogies to topoisomerase I frames the rRNA gene of Tetrahymena.
Exposure of macronuclear chromatin from Tetrahymena thermophila to sodium dodecyl sulfate causes an endogenous nuclease to cleave the extra-chromosomal rDNA at specific sites. All cuts are single-strand cleavages specific to the non-coding strand. Three cleavages map in the central non-transcribed s...
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| Опубликовано в:: | Nucleic Acids Res |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
1983
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| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC326514/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6316268/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/11.22.7661 |
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