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Frizzled1/2/7 signaling directs β-catenin nuclearisation and initiates endoderm specification in macromeres during sea urchin embryogenesis

In sea urchins, the nuclear accumulation of β-catenin in micromeres and macromeres at 4th and 5th cleavage activates the developmental gene regulatory circuits that specify all of the vegetal tissues (i.e. skeletogenic mesoderm, endoderm and non-skeletogenic mesoderm). Here, through the analysis of...

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Autori principali: Lhomond, Guy, McClay, David R., Gache, Christian, Croce, Jenifer C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Company of Biologists 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265065/
https://ncbi.nlm.nih.gov/pubmed/22274701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.072215
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