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Selective inactivation of the 3' to 5' exonuclease activity of Escherichia coli DNA polymerase I by heat.

Heat selectively inactivates the 3' to 5' exonuclease activity of E. coli DNA polymerase I, resulting in reduced dNTP turnover and lower fidelity of replication of homopolymer and natural DNA templates.

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Autores principales: Lecomte, P J, Doubleday, O P
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 1983
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC326498/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6359059/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/11.21.7505
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