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The discovery and development of belimumab: the anti-BLyS–lupus connection

For the first time in more than 50 years, the US Food and Drug Administration has approved a drug specifically for the treatment of systemic lupus erythematosus (SLE). This drug, belimumab (Benlysta), is a human monoclonal antibody that neutralizes the B-cell survival factor, B-lymphocyte stimulator...

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Detalles Bibliográficos
Autores principales: Stohl, William, Hilbert, David M
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264947/
https://ncbi.nlm.nih.gov/pubmed/22231104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.2076
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