Isolation of Alpaca Anti-Hapten Heavy Chain Single Domain Antibodies for Development of Sensitive Immunoassay

Some unique subclasses of Camelidae antibodies are devoid of light chain and the antigen binding site is comprised exclusively of the variable domain of the heavy chain (VHH). Although conventional antibodies dominate current assay development, recombinant VHHs have a high potential as alternative r...

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Autores principales: Kim, Hee-Joo, McCoy, Mark R., Majkova, Zuzana, Dechant, Julie E., Gee, Shirley J., Rosa, Sofia Tabares-da, González-Sapienza, Gualberto G., Hammock, Bruce D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264785/
https://ncbi.nlm.nih.gov/pubmed/22148739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac2030255
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