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PECAM-1 dampens cytokine levels during LPS-induced endotoxemia by regulating leukocyte trafficking

AIMS: To investigate the mechanism by which platelet endothelial cell adhesion molecule 1 (PECAM-1/CD31), an immunoglobulin (Ig)-superfamily cell adhesion and signaling receptor, regulates pro-inflammatory cytokine levels. The purpose of the present investigation was to test the hypothesis that PECA...

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Bibliografiske detaljer
Main Authors: Privratsky, Jamie R., Tilkens, Sarah B., Newman, Debra K., Newman, Peter J.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264774/
https://ncbi.nlm.nih.gov/pubmed/22119535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2011.11.002
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