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Trypanosoma brucei: Inhibition of acetyl-CoA carboxylase by haloxyfop
Trypanosoma brucei, a eukaryotic pathogen that causes African sleeping sickness in humans and nagana in cattle, depends on the enzyme acetyl-CoA carboxylase (ACC) for full virulence in mice. ACC produces malonyl-CoA, the two carbon donor for fatty acid synthesis. We assessed the effect of haloxyfop,...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3264756/ https://ncbi.nlm.nih.gov/pubmed/22119241 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exppara.2011.10.014 |
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