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Trypanosoma brucei: Inhibition of acetyl-CoA carboxylase by haloxyfop

Trypanosoma brucei, a eukaryotic pathogen that causes African sleeping sickness in humans and nagana in cattle, depends on the enzyme acetyl-CoA carboxylase (ACC) for full virulence in mice. ACC produces malonyl-CoA, the two carbon donor for fatty acid synthesis. We assessed the effect of haloxyfop,...

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Bibliografische gegevens
Hoofdauteurs: Vigueira, Patrick A., Paul, Kimberly S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264756/
https://ncbi.nlm.nih.gov/pubmed/22119241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exppara.2011.10.014
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