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Mast cell degranulation distinctly activates trigemino-cervical and lumbosacral pain pathways and elicits widespread tactile pain hypersensitivity

Mast cells (MCs) are tissue resident immune cells that participate in a variety of allergic and other inflammatory conditions. In most tissues, MCs are found in close proximity to nerve endings of primary afferent neurons that signal pain (i.e. nociceptors). Activation of MCs causes the release of a...

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Hlavní autoři: Levy, Dan, Kainz, Vanessa, Burstein, Rami, Strassman, Andrew M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264697/
https://ncbi.nlm.nih.gov/pubmed/22019552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2011.09.016
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