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Loss of the Orphan Nuclear Receptor SHP Is More Pronounced in Fibrolamellar Carcinoma than in Typical Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) remains a major problem in oncology. The molecular mechanisms which underlie its pathogenesis are poorly understood. Recently the Small Heterodimer Partner (SHP), an orphan nuclear receptor, was suggested to be involved as a tumor suppressor in hepatocellular carcinoma...

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Detalhes bibliográficos
Main Authors: Wilczek, Ewa, Szparecki, Grzegorz, Lukasik, Dominika, Koperski, Lukasz, Winiarska, Magdalena, Wilczynski, Grzegorz M., Wasiutynski, Aleksander, Gornicka, Barbara
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264646/
https://ncbi.nlm.nih.gov/pubmed/22292081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030944
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