The Transcription Factor SOX18 Regulates the Expression of Matrix Metalloproteinase 7 and Guidance Molecules in Human Endothelial Cells

BACKGROUND: Mutations in the transcription factor SOX18 are responsible for specific cardiovascular defects in humans and mice. In order to gain insight into the molecular basis of its action, we identified target genes of SOX18 and analyzed one, MMP7, in detail. METHODOLOGY/PRINCIPAL FINDINGS: SOX1...

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Detalhes bibliográficos
Main Authors: Hoeth, Martina, Niederleithner, Heide, Hofer-Warbinek, Renate, Bilban, Martin, Mayer, Herbert, Resch, Ulrike, Lemberger, Christof, Wagner, Oswald, Hofer, Erhard, Petzelbauer, Peter, de Martin, Rainer
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264645/
https://ncbi.nlm.nih.gov/pubmed/22292085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030982
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