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AKT Signaling Mediates IGF-I Survival Actions on Otic Neural Progenitors

BACKGROUND: Otic neurons and sensory cells derive from common progenitors whose transition into mature cells requires the coordination of cell survival, proliferation and differentiation programmes. Neurotrophic support and survival of post-mitotic otic neurons have been intensively studied, but the...

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Detalhes bibliográficos
Main Authors: Aburto, Maria R., Magariños, Marta, Leon, Yolanda, Varela-Nieto, Isabel, Sanchez-Calderon, Hortensia
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264639/
https://ncbi.nlm.nih.gov/pubmed/22292041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030790
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