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Downregulation of RKIP Is Associated with Poor Outcome and Malignant Progression in Gliomas

Malignant gliomas are highly infiltrative and invasive tumors, which precludes the few treatment options available. Therefore, there is an urgent need to elucidate the molecular mechanisms underlying gliomas aggressive phenotype and poor prognosis. The Raf Kinase Inhibitory protein (RKIP), besides r...

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Detalhes bibliográficos
Main Authors: Martinho, Olga, Granja, Sara, Jaraquemada, Teresa, Caeiro, Cláudia, Miranda-Gonçalves, Vera, Honavar, Mrinalini, Costa, Paulo, Damasceno, Margarida, Rosner, Marsha R., Lopes, José M., Reis, Rui M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264629/
https://ncbi.nlm.nih.gov/pubmed/22292035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030769
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