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Arousal of Cancer-Associated Stroma: Overexpression of Palladin Activates Fibroblasts to Promote Tumor Invasion

BACKGROUND: Cancer-associated fibroblasts, comprised of activated fibroblasts or myofibroblasts, are found in the stroma surrounding solid tumors. These myofibroblasts promote invasion and metastasis of cancer cells. Mechanisms regulating the activation of the fibroblasts and the initiation of invas...

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Autors principals: Brentnall, Teresa A., Lai, Lisa A., Coleman, Joshua, Bronner, Mary P., Pan, Sheng, Chen, Ru
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264580/
https://ncbi.nlm.nih.gov/pubmed/22291919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030219
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