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An autoimmune disease prevented by anti-retroviral drugs
BACKGROUND: Both Aicardi-Goutières syndrome, a Mendelian mimic of congenital infection, and the autoimmune disease systemic lupus erythematosus can result from mutations in the gene encoding the enzyme Trex1. In mice, the absence of Trex1 causes severe myocarditis. The enzyme is thought to degrade e...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3264515/ https://ncbi.nlm.nih.gov/pubmed/22067273 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-8-91 |
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