The Insulator Protein CTCF Binding Sites in the orf73/LANA Promoter Region of Herpesvirus Saimiri Are Involved in Conferring Episomal Stability in Latently Infected Human T Cells

Herpesviruses establish latency in suitable cells of the host organism after a primary lytic infection. Subgroup C strains of herpesvirus saimiri (HVS), a primate gamma-2 herpesvirus, are able to transform human and other primate T lymphocytes to stable growth in vitro. The viral genomes persist as...

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Main Authors: Zielke, Katrin, Full, Florian, Teufert, Natascha, Schmidt, Monika, Müller-Fleckenstein, Ingrid, Alberter, Barbara, Ensser, Armin
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2012
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264369/
https://ncbi.nlm.nih.gov/pubmed/22130528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06295-11
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