Human Herpesvirus 8 Viral Interleukin-6 Interacts with Splice Variant 2 of Vitamin K Epoxide Reductase Complex Subunit 1

Viral interleukin-6 (vIL-6) specified by human herpesvirus 8 is, unlike its cellular counterpart, secreted very inefficiently and can signal via vIL-6(2):gp130(2) signaling complexes from the endoplasmic reticulum (ER) compartment. Intracellular, autocrine activities of vIL-6 are important for propr...

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Bibliographic Details
Main Authors: Chen, Daming, Cousins, Emily, Sandford, Gordon, Nicholas, John
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264350/
https://ncbi.nlm.nih.gov/pubmed/22130532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05782-11
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