Streptococcus suis Capsular Polysaccharide Inhibits Phagocytosis through Destabilization of Lipid Microdomains and Prevents Lactosylceramide-Dependent Recognition

Streptococcus suis type 2 is a major swine pathogen and a zoonotic agent, causing meningitis in both swine and humans. S. suis infects the host through the respiratory route, reaches the bloodstream, and persists until breaching into the central nervous system. The capsular polysaccharide (CPS) of S...

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Bibliographic Details
Main Authors: Houde, Mathieu, Gottschalk, Marcelo, Gagnon, Fleur, Van Calsteren, Marie-Rose, Segura, Mariela
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
Subjects:
Molecular Pathogenesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264306/
https://ncbi.nlm.nih.gov/pubmed/22124659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05734-11
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