HIV-1 Protease Inhibitors and Clinical Malaria: a Secondary Analysis of the AIDS Clinical Trials Group A5208 Study

HIV-1 protease inhibitors (PIs) have antimalarial activity in vitro and in murine models. The potential beneficial effect of HIV-1 PIs on malaria has not been studied in clinical settings. We used data from Adult AIDS Clinical Trials Group A5208 sites where malaria is endemic to compare the incidenc...

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Détails bibliographiques
Auteurs principaux: Porter, Kimberly A., Cole, Stephen R., Eron, Joseph J., Zheng, Yu, Hughes, Michael D., Lockman, Shahin, Poole, Charles, Skinner-Adams, Tina S., Hosseinipour, Mina, Shaffer, Doug, D'Amico, Ronald, Sawe, Frederick K., Siika, Abraham, Stringer, Elizabeth, Currier, Judith S., Chipato, Tsungai, Salata, Robert, McCarthy, James S., Meshnick, Steven R.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2012
Sujets:
Antiviral Agents
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264273/
https://ncbi.nlm.nih.gov/pubmed/22123685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05322-11
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