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Potent Antiviral Activity of Topoisomerase I and II Inhibitors against Kaposi's Sarcoma-Associated Herpesvirus

The lytic DNA replication of Kaposi's sarcoma-associated herpesvirus (KSHV) initiates at an origin (ori-Lyt) and requires trans-acting elements, both viral and cellular. We recently demonstrated that several host cellular proteins, including topoisomerases I and II (Topo I and II), are involved...

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Detaylı Bibliyografya
Asıl Yazarlar: González-Molleda, Lorenzo, Wang, Yan, Yuan, Yan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264263/
https://ncbi.nlm.nih.gov/pubmed/22106228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05274-11
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