Identification of BPR3P0128 as an Inhibitor of Cap-Snatching Activities of Influenza Virus

The aim of this study was to identify the antiviral mechanism of a novel compound, BPR3P0128. From a large-scale screening of a library of small compounds, BPR3P compounds were found to be potent inhibitors of influenza viral replication in Madin–Darby canine kidney (MDCK) cells. BPR3P0128 exhibited...

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Detalhes bibliográficos
Main Authors: Hsu, John T.-A., Yeh, Jiann-Yih, Lin, Ta-Jen, Li, Mei-ling, Wu, Ming-Sian, Hsieh, Chung-Fan, Chou, Yao Chieh, Tang, Wen-Fang, Lau, Kean Seng, Hung, Hui-Chen, Fang, Ming-Yu, Ko, Shengkai, Hsieh, Hsing-Pang, Horng, Jim-Tong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264257/
https://ncbi.nlm.nih.gov/pubmed/21930871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00125-11
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