Vancomycin AUC(24)/MIC Ratio in Patients with Complicated Bacteremia and Infective Endocarditis Due to Methicillin-Resistant Staphylococcus aureus and Its Association with Attributable Mortality during Hospitalization

Methicillin-resistant Staphylococcus aureus (MRSA) is a common cause of complicated bacteremia (CB) and infective endocarditis (IE). The gold standard treatment for these infections is vancomycin. A vancomycin area under the concentration-time curve from 0 to 24 h (AUC(24))/MIC ratio of >400 has...

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Bibliografiske detaljer
Main Authors: Brown, Jack, Brown, Kristen, Forrest, Alan
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264249/
https://ncbi.nlm.nih.gov/pubmed/22123681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05609-11
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