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In Vivo Growth Rates Are Poorly Correlated with Phage Therapy Success in a Mouse Infection Model

Two classes of phages yield profoundly different levels of recovery in mice experimentally infected with an Escherichia coli O18:K1:H7 strain. Phages requiring the K1 capsule for infection (K1-dep) rescue virtually all infected mice, whereas phages not requiring the capsule (K1-ind) rescue modest nu...

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Detalles Bibliográficos
Main Authors: Bull, J. J., Otto, G., Molineux, I. J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264239/
https://ncbi.nlm.nih.gov/pubmed/22106213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05842-11
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