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Long-range conformational transition in yeast tRNAPhe, induced by the Y-base removal and detected by chloroacetaldehyde modification.

Chemical modification was used to study the conformational changes occurring in yeast tRNAPhe after the Y-base excision. The chemical probe was the adenine- and cytosine-specific reagent chloroacetaldehyde. Comparison of the modification patterns in tRNAPhe and tRNAPhe-Y shows that seven bases, aden...

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Bibliographic Details
Main Authors: Krzyzosiak, W J, Ciesiołka, J
Format: Artigo
Language:Inglês
Published: 1983
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC326423/
https://ncbi.nlm.nih.gov/pubmed/6356038
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