E1210, a New Broad-Spectrum Antifungal, Suppresses Candida albicans Hyphal Growth through Inhibition of Glycosylphosphatidylinositol Biosynthesis

Continued research toward the development of new antifungals that act via inhibition of glycosylphosphatidylinositol (GPI) biosynthesis led to the design of E1210. In this study, we assessed the selectivity of the inhibitory activity of E1210 against Candida albicans GWT1 (Orf19.6884) protein, Asper...

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Xehetasun bibliografikoak
Egile Nagusiak: Watanabe, Nao-aki, Miyazaki, Mamiko, Horii, Takaaki, Sagane, Koji, Tsukahara, Kappei, Hata, Katsura
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2012
Gaiak:
Mechanisms of Action: Physiological Effects
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264227/
https://ncbi.nlm.nih.gov/pubmed/22143530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00731-11
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