Pharmacological and Patient-Specific Response Determinants in Patients with Hospital-Acquired Pneumonia Treated with Tigecycline

Pharmacokinetic and clinical data from tigecycline-treated patients with hospital-acquired pneumonia (HAP) who were enrolled in a phase 3 clinical trial were integrated in order to evaluate pharmacokinetic-pharmacodynamic (PK-PD) relationships for efficacy. Univariable and multivariable analyses wer...

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Bibliografiske detaljer
Main Authors: Bhavnani, Sujata M., Rubino, Christopher M., Hammel, Jeffrey P., Forrest, Alan, Dartois, Nathalie, Cooper, C. Angel, Korth-Bradley, Joan, Ambrose, Paul G.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264202/
https://ncbi.nlm.nih.gov/pubmed/22143524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01615-10
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