Clinical Significance of Quantifying Pneumocystis jirovecii DNA by Using Real-Time PCR in Bronchoalveolar Lavage Fluid from Immunocompromised Patients

Quantitative PCR (qPCR) is more sensitive than microscopy for detecting Pneumocystis jirovecii in bronchoalveolar lavage (BAL) fluid. We therefore developed a qPCR assay and compared the results with those of a routine immunofluorescence assay (IFA) and clinical data. The assay included automated DN...

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Détails bibliographiques
Auteurs principaux: Botterel, Françoise, Cabaret, Odile, Foulet, Françoise, Cordonnier, Catherine, Costa, Jean-Marc, Bretagne, Stéphane
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2012
Sujets:
Mycology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264196/
https://ncbi.nlm.nih.gov/pubmed/22162560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.06036-11
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